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Illumina company sign outside its headquarters at 5200 Illumina Way
Photo: Investing.com

Illumina Stock Falls 12% After Hours on Revenue Miss

Illumina Investor Relations2 min read6 sources

Why is Illumina stock down today?

Illumina (ILMN) stock fell about 12% to $255.88 in after-hours trading on Thursday after quarterly revenue of $1.13 billion missed the $1.15 billion forecast and China sales stayed flat.

Key numbers

Q3 revenue (reported)$1.13B+4.2% YoY; forecast $1.15B
Adjusted profit per share$1.44vs $1.36 forecast
After-hours price$255.88-11.78% from $290.06 close (some reports say 13%)
2026 revenue guidance$4.64B-$4.66Braised from $4.60B-$4.64B
China effect on growth-0.1%flat; call remarks differ (per [2])

What happened

Illumina (ILMN) stock fell about 12% to $255.88 in after-hours trading on Thursday after quarterly revenue of $1.13 billion missed the $1.15 billion forecast and China sales stayed flat. Sales rose 4.2% from a year ago, and profit of $1.44 a share beat the $1.36 forecast. Biopharma and university labs bought fewer machines, and China sales were flat, a 0.1% drag on growth. Illumina still raised its own yearly forecast (guidance) to $4.64 billion to $4.66 billion in sales.

Why it matters

Illumina makes the machines and supplies used to read DNA, so its results show how much labs and hospitals are spending on genetic testing. The drop shows investors can care more about slowing sales growth than a profit beat. Hospital testing demand stayed strong, but research spending weakened. China also remains a problem, since it has put Illumina on a government blacklist (the Unreliable Entities List).

Who this affects

Marketbearish
Low impact
Healthcare-tool investors face a sharp one-day loss.
Companybearish
Medium impact
Shareholders lost about 12% after hours despite raised outlook.
Competitorsneutral
Low impact
Rivals may face the same weak lab spending.
Industrymixed
Medium impact
Research-lab tool makers face weaker demand; clinical testing stays strong.

Illumina vs Thermo Fisher Scientific, Pacific Biosciences

IlluminaILMN2026-10-29+4.2%-11.8%
Thermo Fisher ScientificTMO2026-10-21+9%—
Pacific BiosciencesPACBDue 2026-11-04——

As of 2026-10-30

How we got here

  1. Thermo Fisher reports Q3 revenue up 9% to $12.14 billion.

  2. Illumina shares close at $290.06 before results.

  3. Illumina reports Q3 and raises its 2026 sales and profit guidance.

  4. Shares drop 11.78% to $255.88 in after-hours trading.

What to watch

  • Friday regular-session trading shows whether the after-hours drop holds.2026-10-30
  • Pacific Biosciences reports Q3 results, another read on research-lab spending.2026-11-04
  • Illumina's 2027 outlook, with high-single-digit consumables growth hinted.Q4 2026

Educational content only. Not investment advice.

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