
Vaxcyte Stock Jumps 31% After Positive Phase 3 Data
Vaxcyte (PCVX) closed at $73.82 as its VAX-31 shot held up against Pfizer's and Merck's shots in a large trial
Daily Digest
Daily Digest

Vaxcyte (PCVX) closed at $73.82 as its VAX-31 shot held up against Pfizer's and Merck's shots in a large trial

Treasury yields climbed again Monday, with the 10-year at 5.34% and the 30-year near 5.7%, as German, French, Italian and UK government bonds fell in step.

Germany's RobCo (Munich robotics) hit a $1B+ valuation in a roughly $40M secondary share sale, mostly employee shares, with Cherry Ventures and European Tech joining.
Accenture (ACN) slid to about $200 a day after its best session ever as investors locked in gains.
SpaceX (SPCX) traded up about 5% Monday on a Morgan Stanley note after its three-launch run.
Over 2 billion people drink coffee every day - and the entire supply chain rests on a handful of frost-prone growing regions and 20 million small farmers receiving 5–10% of the retail price. A short walkthrough of Arabica vs Robusta, why a single Brazilian frost can cut the following year's supply by 20–30%, how the 3–4 year tree maturity cycle creates boom-bust pricing, and what climate change means for Colombia, Kenya, and Ethiopia.

Skyworks (SWKS) completed its Qorvo combination on Oct. 5 after all approvals, forming a U.S. radio-frequency chipmaker with $500M+ in targeted synergies.
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Hewlett Packard Enterprise (HPE) landed a $1.2B AMD rack order, and Teradyne (TER) rose 8% on AI test tools

Bitcoin above $86,700 lifts Coinbase, Circle and Strategy 3-4% as U.S. spot Bitcoin ETFs log a third straight week of net inflows and $90,000 is in focus.

Brent topped $100 and crude rose about 2% after China halted October fuel exports, tightening a diesel market strained by the Middle East war and Russian curbs.

Israeli AI marketing/sales startup enso raised a $15M Series A led by MoreTech Ventures, with NFX participating. Total funding is now $23M.
Commodity index funds let you own a diversified slice of raw materials - oil, metals, agriculture - without ever touching a futures contract yourself. A short walkthrough of how funds like the S&P GSCI and Bloomberg Commodity Index work, why roll drag silently erodes 2–5% of returns annually in contango markets, the difference between ETFs and mutual fund structures, and what energy-heavy weightings mean for what you're actually buying.
Vistra (VST) trades near $146 as the US plans a $4B loan to boost output at three nuclear plants.
RXO (RXO) agrees to a $5.8B cash-and-stock sale as C.H. Robinson (CHRW) shares drop 13% on dilution fears.

Vaxcyte (PCVX) shares jumped about 50% after VAX-31 met every primary endpoint in a pivotal Phase 3 trial against Pfizer's Prevnar 20 and Merck's Capvaxive.

C.H. Robinson (CHRW) agreed to buy freight broker RXO for $5.8 billion, or $30.25 a share in cash and stock, sending RXO shares up more than 20% on Monday.

Schneider Electric (SU.PA) agreed to pay $205 a share in cash, a 42% premium, for US software maker PTC.

The Brazil ETF EWZ rose about 12-13% and the real gained 5% after Flavio Bolsonaro led Lula 47% to 45% in the first round, setting up an October 25 runoff.
The shape of a commodity's futures curve tells you almost everything about the current state of the market. A short walkthrough of contango and backwardation, the convenience yield that explains why physical holders accept lower returns than futures imply, how the curve responds within hours to supply disruptions and inventory data, and why persistent contango quietly drains 2–5% annually from buy-and-hold investors.

Haifa-based HydroSight came out of stealth with a $5M Seed led by StageOne Ventures. It builds an AI platform for mapping the seabed.
Saudi oil income is $60B a year above its pre-war level as Aramco (2222.SR) ships crude around Hormuz

IG Group (IGG) shares sank 23% after it cut its 2026 revenue growth outlook on weaker OTC retention, pulling rivals CMC Markets and Plus500 sharply lower.

Nikkei 225 (^N225) briefly topped 70,000 as soft US jobs data cut Fed hike odds and lifted chip stocks.

Iran-linked strikes have hit at least six ships near the Strait of Hormuz since Sept. 28, even as Gulf crude exports climbed back above pre-war levels.

Brent crude (BZ=F) trades near $102 as 10,000 more US troops head to the Gulf ahead of possible Iran strikes

Teradyne gained about 8% on new AI memory and photonics test platforms while HPE rose about 7% on a $1.2 billion Vultr order, lifting AI hardware stocks.

US AI agent startup Instinct raised a $1B Series C at a $10B valuation. Sequoia, Benchmark and Coatue led it, and the invite-only service launched only in August.

Reliance (RELIANCE.NS) unit Jio targets a $143B-plus value, with an Oct. 21 launch, mostly to repay debt.

FICO stock jumped 11% Thursday and fell about 8% Friday as the FHFA opened U.S. mortgage scoring to VantageScore and weighed a two-bureau credit data rule.
Commodity ETFs can track an index perfectly and still deliver returns far below the underlying commodity price. The culprit is contango - the normal market structure where future prices exceed spot prices. A short walkthrough of why storage, insurance, and financing costs create an upward-sloping curve, how rolling expiring contracts into pricier ones drains 5–15% annually, what super-contango is, and how professional traders exploit the spread.

Fair Isaac (FICO) is down more than 60% this year as regulators open mortgage scoring to rival VantageScore

SpaceX (SPCX) rose 7.4% to $158.96 after Crew-13, Transporter-18 and NROL-97 launched within 13 hours, carrying Google's first orbital AI test satellite.

iShares MSCI Brazil ETF (EWZ) rose to $42.12 from $38.19 as Bolsonaro led Lula 47% to 45%; runoff is Oct. 25.

Schneider Electric agreed to buy PTC for $22.6 billion in cash at $205 a share, a 42% premium, but its own stock fell 7.6% on financing and valuation concerns.

US AI infrastructure startup PaleBlueDot AI raised a $200M Series C at a $3.2B valuation. It was founded in 2026 and raised a $150M Series B in January.

Rocket Lab (RKLB) booked 20 Synspective launches; McCormick (MKC) also rose premarket on a Q3 beat.
Copper has a PhD in economics - prices rise with global growth and fall sharply in recessions, making it the commodity market's most reliable macro barometer. A short walkthrough of why Chile and Peru supply 40% of global output, how China's 50% share of demand turns every construction slowdown into a price shock, why EVs need four times more copper than petrol cars, and what the energy transition means for long-term supply and demand.

Houthi forces holding Mokha and Perim threaten the Red Sea bypass for Gulf oil as Saudi sites are hit, keeping the crude oil price near $103 a barrel.

Brent crude (BZ=F) ended Friday at $102.25 as the US rejected Iran's terms to reopen the Strait of Hormuz
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